Overview

Amazon blocks sellers with Error 100328 when they attempt to list prescription drugs or regulated medical items without the required authorization. The error appears during creation or editing of such listings and signals that Amazon’s compliance system has detected missing or invalid healthcare credentials. Sellers must address the gap to avoid listing removal and potential account penalties.

Key Points

• Authorization required — Only sellers who have received explicit approval from Amazon can publish prescription or medical product listings; a pharmacy license or equivalent credential is mandatory.
• Multiple trigger points — The error shows up when adding a new prescription item, updating an existing drug listing, or when previously submitted credentials have expired or were never uploaded.
• Specific documentation needed — Amazon expects a current medical or pharmacist license, a valid pharmaceutical distributor certificate, or a certified medical device manufacturer’s accreditation on file.
• Unauthorized listings are removed — Any active listing for a prescription medication that lacks proper approval will be automatically deactivated and may be flagged for removal from the seller’s inventory.
• Compliance enforcement is strict — Repeated attempts to list restricted products without authorization can lead to warnings, suspension of the health‑related categories, or broader account actions.

How to Resolve Error 100328

1. Confirm eligibility — Review Amazon’s Restricted Products policy to verify that your business type (e.g., licensed pharmacy, authorized distributor, certified medical device maker) matches one of the approved entity categories. Example: A seller operating a wholesale pharmacy checks the policy and sees that only entities with a state pharmacy license are permitted to list prescription antibiotics.
2. Gather required credentials — Collect all relevant documents, such as a state‑issued medical license, pharmacist registration number, FDA registration for devices, or a distributor’s wholesale drug license. Ensure each document is current and matches the name and address on your seller account.